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Research Interest

 

1. Free radical initiated peptide sequencing (FRIPS)

 

 

 

 

7. Photodissociation of TEMPO-modified peptides for radical-induced peptide sequencing. Marshall, D. L.; Hansen, C. S.; Trevitt, A. J.; Blanksby, S. J.; Oh, H. B.  in preparation. (2013).

6. Density Functional Theory (DFT) study of gas-phase O-C bond dissociation energy of models for o-TEMPO-Bz-C(O)-Peptide: A model study for free radical initiated peptide sequencing (FRIPS). Kwon, G. M.; Kwon, H. S.; Lee, J. H.; Sang Yun Han; Moon, B. J.*; Oh, H. B.*, Sung, B. .J.*  submitted to Bull. Korean Chem. Soc. (2013). Retirement special issue for Prof. M. S. Kim (Seoul National University). 

5. Radical-driven peptide backbone dissociation tandem mass spectrometry. Oh, H. B.*, Moon, B. J. Mass Spectrom. Rev. (2013) in revision.

4. One-step peptide backbone fragmentations in negative ion free radical initiated peptide sequencing mass spectrometry. Lee, J. H.; Park, H. Y.; Kwon, H. S.; Kwon, K. M.; Sung, B. J.; Moon, B. J.; Kim, H. I.; Oh, H. B.* Anal. Chem. 2013, 85(15), 7044-7051.

3. Radical-driven peptide backbone dissociation tandem mass spectrometry. Oh, H. B.*, Moon, B. J. submitted to Mass Spectrom. Rev. (2012).

2. Disulfide bond cleavage by TEMPO-free radical initiated peptide sequencing mass spectrometry. Lee, M. H.; Lee, Y. J.; Kang, M. H.; Park, H. Y.; Seong, Y. M.;  Sung, B. J.; Moon, B. J.; Oh, H. B.*  J. Mass Spectrom. 2011, 46(8), 830-839.

1. Gas phase peptide sequencing by TEMPO mediated radical generation, Lee, M. H.; Kang, M. H.; Moon, B. J.; Oh, H. B. Analyst, 2009, 134, 1706-1712. DOI:10.1039/b904115j.

 

2. IR Photodissociation Spectroscopy

 

11. Structures of proton-bound guanine and cytosine DNA base homodimers and guanine-cytosine base pair studied by infrared photodissociation spectroscopy. Seong, Y. M.; Park, S. J.; Ahn, H. K.; Rhee, B. K.; Han, S. Y.; Oh, H. B.* in preparation for J. Phys. Chem. A (2013).

10. Infrared photodissociation spectroscopy and density functional theory (DFT) studies of protonated permethylated β-Cyclodextrin-water noncovalent complexes. Park, S. J.#; Lee, S. S.#; Kim, J.-Y.; Kim, H. R.; Lee, S. Y.*; Oh, H. B.* in preparation for Phys Chem Chem Phys (2013).

9. An anomalous dissociation of protonated cluster ions of DNA guanine-cytosine base-pair. Seong, Y. M.; Han, S. Y.; Jo, S.-C.; Oh, H. B.*  Mass Spectrom. Lett. 2011, 2(3), 69-71.

8. Numerous isomers of protonated serine octamer ions characterized by infrared photodissociation spectroscopy. Kong, X.; Lin, C.; Infusini, G.; Oh, H. B.; Breuker, K.; Wu, C. C.; Charkin, O. P.; Chang, H.-C.; McLafferty, F. W. ChemPhysChem 2009, web-published, DOI: 10.1002/cphc.200900564.

7. Base-pair Interactions in the gas-phase proton-bonded complexes of G+G and C+GC. Han, S. Y.; Lee, S. H.; Chung, J.; Oh, H. B. J. Chem. Phys. 2007, 127, 245102-245111.6

6. Theoretical study of the ionic hydrogen bond in the isolated proton-bound dimer of cytosine. Han, S. Y.; Oh, H. B. Chem. Phys. Lett. 2006, 432, 269-274.

5. The Structures and Proton Transfer Barriers in the Proton-Bound Homodimers of Aromatic Molecular Bases: Implications of Zero-Point Energies on the Proton-Transfer Reaction. Han, S. Y.; Lee, Sang Hak; Oh, H. B. Bull. Korean Chem. Soc. 2006, 27, 1903-1906.

4. Tautomerism and Isomerism of Guanine-Cytosine DNA Base Pair: Ab initiio and Density Function Theory Approaches. Chung, G. S.; Oh, H. B.; Lee, D. H. J. Mol. Struct. (Theochem), 2005, 730, 241-249.

3. Infrared Photodissociation Spectroscopy of Electrosprayed Ions in a Fourier-Transform Mass Spectrometer. Oh, H-B.; Lin, C.; Hwang, H.; Zabrouskov V.; Zhai, H.; Carpenter, B. K.; McLafferty F. W. J. Am. Chem. Soc. 2005, 127 (11), 4076-4083.

2. Nonergodic and Conformational Control of the Electron Capture Dissociation of Protein Cations. Breuker, K.; Oh, H-B.; Lin, C.; Carpenter, B. K.; McLafferty F. W. Proc. Natl. Acad. Sci. USA 2004, 101, 14011-14016.

1. Secondary and Tertiary Structures of Gaseous Protein Ions Characterized by Electron Capture Dissociation Mass Spectrometry and Photofragment Spectroscopy. Oh, H-B.; Breuker, K; Sze, S. K.; Ying, G.; Carpenter, B. K.; McLafferty, F. W. Proc. Natl. Acad. Sci. USA, 2002, 99, 15863-15869.

 

3. ECD of peptide/proteins, EDD of carbohydrates

 

 

19. Exploring the structural characterisitcs of melittin ions in the gas phase by electron capture dissociation mass spectrometry and molecular dynamics simulations. Shim, S.; Seok, C. O.*; Yu, S. H.; Lee, S. Y.; Nam, J. J.; Oh, H. B.* in preparation for Phys Chem Chem Phys (2013).

18. MALDI in-source decay studies of polyamidoamine dendrimers. So, H. R.; Lee, J.; Han, S. Y.*; Oh, H. B.*  J. Am. Soc. Mass Spectrom. 2012, 23(10), 1821-1825.

17. Protein analysis using a combination of an online monolithic trypsin-immobilized enzyme reactor and collisionally-activated dissociation and electron transfer dissociation dual tandem mass spectrometry. Hwang, H. J.; Cho, K.; Kim, J.Y.; Kim, Y.H.; Oh, H. B.* Bull. Korean Chem. Soc. 2012, 33(10), 3233-3240

16. Multivariate analysis of electron detachment dissociation (EDD) and Infrared multiphoton dissociation mass spectra of Heparan sulfate (HS) tetrasaccharides differing only in hexuronic acid stereochemistry. Oh, H. B.*; Leach, F.; Arungundram, S.; Kanar Al-Mafragi; Venot, A.; Boons, Geert-Jan; Amster, J. I.* J. Am. Soc Mass Spectrom. 2011, 22, 582-590.

15. Characterization of Permethylated β-Cyclodextrin-Peptide Noncovalently Bound Complexes Using Electron Capture Dissociation Mass Spectrometry (ECD MS). Lee, S. Y.; Park, S. J.; Ahn, S. H.; Oh, H. B. Int. J. Mass Spectrom. 2009, 279, 47-52.

14. Electron Capture Dissociation of Proteins Initiated by Photoelectrons Generated from 266 nm UV Laser Radiation on an ICR Cell Wall. Lee, S. Y.; Park, S. J.; Lee, Y. W.; Oh, H. B.; Kang, H.; Cho, K. H.; Ahn, W. K.; Rhee, B. K. Bull. Korean Chem. Soc. 2008, 29(9), 1673.

13. Neutral loss of a Phosphate moiety in a Hot Electron Capture Dissociation, Lee, S.; Ahn, S. H.; Yim, Y. H.; Kim, B. J.; So, H. Y.; Oh, H. B. Bull. Korean Chem. Soc. 2007, 28(7), 1195-1198.

12. Electron caputure dissociation Mass Spectrometry (ECD MS) of Peptide Cations Containing a Lysine Homologue: A Mobile Proton Model for Explaining the Observation of b-type of Product Ions. Lee, S. Y.; Chung, G. S.; Kim, J. D.; Oh, H. B. Rapid Commun. Mass Spectrom. 2006, 20, 3167-3175.

11. Evaluation of the Internal Temperature of 8.6 kDa Protein Cations Exposed to a Hot Dispenser Cathode Employed in the Electron Capture Dissociation Mass Spectrometry, Yim, Y. H.; Kim, B. J.; Ahn, S. H.; So, H. Y.; Lee, S. Y.; Oh, H. B. Rapid Commun. Mass Spectrom. 2006, 20, 1918-1924.

10. Observation of Pronounced b ions in the Electron Capture Dissociation Mass Spectrometry of Polyamidoamine (PAMAM) Dendrimer Ions with amide-bond Functionalities. Lee, S. Y.; Han, S. Y.; Lee, T. G.; Lee, D. H.; Chung, G. S.; Oh, H. B., J. Am. Soc. Mass Spectrom. 2006, 17, 536-543.

9. A variety of activation methods employed in “activated-ion” electron capture dissociation mass spectrometry: a test against Bovine ubiquitin 7+ ions. Oh, H. B.; McLafferty, F. W. Bull. Korean Chem. Soc. 2006, 27, 389-394.

8. Comparable Electron Capture Efficiencies for Various Protonated Sites on the 3rd Generation Poly(Propylene Imine) Dendrimers: Probed by SORI-CAD and Electron Capture Dissociation Mass Spectrometry (ECD MS). Han, S. Y.; Lee, S. Y.; Oh, H. B. Bull. Korean Chem. Soc. 2005, 26, 740-746.

7. Nonergodic and Conformational Control of the Electron Capture Dissociation of Protein Cations. Breuker, K.; Oh, H-B.; Lin, C.; Carpenter, B. K.; McLafferty F. W. Proc. Natl. Acad. Sci. USA 2004, 101, 14011-14016.

6. Plasma Electron Capture Dissociation of Large Gaseous Ions. Sze, S. K.; Ge, Y.; Oh, H-B.; McLafferty, F. W. Anal. Chem. 2003, 75, 1599-1603.

5. Top Down Characterization of Secreted Proteins from Mycobacterium Tuberculosis by Electron Capture Dissociation Mass Spectrometry. Ge, Y.; ElNaggar, M.; Sze, S. K.; Oh, H-B.; McLafferty, F. W. J. Am. Soc. Mass. Spectrom. 2003, 14, 253-261.

4. Secondary and Tertiary Structures of Gaseous Protein Ions Characterized by Electron Capture Dissociation Mass Spectrometry and Photofragment Spectroscopy. Oh, H-B.; Breuker, K; Sze, S. K.; Ying, G.; Carpenter, B. K.; McLafferty, F. W. Proc. Natl. Acad. Sci. USA, 2002, 99, 15863-15869.

3. Detailed Unfolding and Folding of Gaseous Ubiquitin Ions Characterized by Electron Capture Dissociation. Breuker, K.; Oh, H-B.; Horn, D. M.; Cerda, B. A.; McLafferty, F. W. J. Am. Chem. Soc. 2002, 124, 6407-6420.

2. Hydrogen Atom Loss in Electron Capture Dissociation: A FT-ICR Study with Single Isotopomeric Ubiquitin Ions. Breuker K.; Oh, H-B.; Cerda, B. A.; Horn, D. M.; McLafferty, F. W. Eur. J. Mass Spectrom. 2002, 8, 177-180.

1. Top Down Mass Spectrometry of a 29 kDa Protein for Characterization of Any Posttranslational Modification to Within One Residue. Sze, S. K.; Ge, Y.; Oh, H-B.; McLafferty, F. W. Proc. Natl. Acad. Sci. USA 2002, 99, 1774-1779

 

4. Nano sol-gel protein entrapped affinity Chromatography

 

2. A multidimensional system for phosphopeptide analysis using TiO2 enrichment and ion-exchange chromatography with mass spectrometry. Cho, K.; Yoo J.; Kim, J. Y.; Oh, H. B.*; Yoo, J. S.* Bull. Korean Chem. Soc. 2012, 33(10), 3298-3302.

1. Protein analysis using a combination of an online monolithic trypsin-immobilized enzyme reactor and collisionally-activated dissociation and electron transfer dissociation dual tandem mass spectrometry. Hwang, H. J.; Cho, K.; Kim, J.Y.; Kim, Y.H.; Oh, H. B.* Bull. Korean Chem. Soc. 2012, 33(10), 3233-3240

 

5. Lipid mass spectrometry


 

 

 

3. Synergetic  and antagonistic role of natural antioxidant in the autoxidation of soybean oil. Lee, K.-W.; Li, J.; Kim, Y.-W.; Chung, K.-W.; Lee, Y. J.; Oh, H. BJ. Ind. Eng. Chem. 2011, 17, 537-542.

2. High accuracy mass measurement approach in the identification of phospholipids in lipid extracts: 7 T Fourier-transform mass spectrometry and MS/MS validation. Yu, S. H.; Park, S. J.; Lee, Y. W.; Cho, K.; Kim, Y. H. Oh, H. B.* Bull. Korean Chem. Soc.  2011, 32, 1170-1178.

1. Identification of Phospholipids Molecular Species in Procine Brain Extracts Using High Mass Accuracy of 4.7 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, Yu, S. H.; Cho, K.; Kim, Y. H.; Park, S. J.; Kim, J. D.; Oh, H. B., Bull. Korean Chem. Soc. 2006, 27(5), 793-796.

 

6. Noncovalent interactions in proteins

 

 

3. Mass spectrometry based determination of Zinc(II) ion affinity to zinc-finger peptides. Park, S. J.; Lee, C. S.; Park, S. S.; Oh, H. B.* in preparation for Rapid Commun. Mass Spectrom. (2013).

2. Examination of various metal sources for reducing nonspecific zin finger-Zn2+ complex formation in ESI mass spectrometry. Park, S. J.; Park, S. H.; Oh, J. Y.; Han, S. Y.; Jo, K. B.; Oh, H. B.* Mass Spectrom. Lett. 2012, 3(3), 82-85. 

1. Zinc-finger motif noncovalent interactions with double stranded DNAs characterized by negative ion electrospray ionization mass spectrometry. Park, S. J.; Cho, K. B.*; Oh, H. B.*  Analyst, 2011, 136(18), 3739-3746.  (Back cover image) 

 

7. MALDI-mass spectrometry

 

2. MALDI-TOF analysis of polyhexamethylene guanidine (PHMG) oligomers used as a commericial antibacterial humidifier disinfectant. Hwang, H. J.; Nam, J. J.; Yang, S. I.; Kwon, J-.H.*; Oh, H. B.*  Bull. Korean. Chem. Soc. 2013, 34(6), 1708-1714.

1. MALDI in-source decay studies of polyamidoamine dendrimers. So, H. R.; Lee, J.; Han, S. Y.*; Oh, H. B.*  J. Am. Soc. Mass Spectrom. 2012, 23(10), 1821-1825

 

8. PolymerI-mass spectrometry

 

5. Tandem mass spectrometry analysis of isosorbide-1,4-cyclohexane polyester oligomer cations using ion-trap mass spectrometry. Lee, J. H.; Lee, S. I.; Yoon, D. H.; Yoon, W. J.; Im, S. S.*; Moon, B. J.; Oh, H. B.*  Rapid Commun. Mass Spectrom. 2013, 27(17), 1913-1918.

4. MALDI-TOF analysis of polyhexamethylene guanidine (PHMG) oligomers used as a commericial antibacterial humidifier disinfectant. Hwang, H. J.; Nam, J. J.; Yang, S. I.; Kwon, J-.H.*; Oh, H. B.*  Bull. Korean. Chem. Soc. 2013, 34(6), 1708-1714.

3. MALDI in-source decay studies of polyamidoamine dendrimers. So, H. R.; Lee, J.; Han, S. Y.*; Oh, H. B.*  J. Am. Soc. Mass Spectrom. 2012, 23(10), 1821-1825.

2. Observation of Pronounced b ions in the Electron Capture Dissociation Mass Spectrometry of Polyamidoamine (PAMAM) Dendrimer Ions with amide-bond Functionalities. Lee, S. Y.; Han, S. Y.; Lee, T. G.; Lee, D. H.; Chung, G. S.; Oh, H. B., J. Am. Soc. Mass Spectrom. 2006, 17, 536-543.

1. Comparable Electron Capture Efficiencies for Various Protonated Sites on the 3rd Generation Poly(Propylene Imine) Dendrimers: Probed by SORI-CAD and Electron Capture Dissociation Mass Spectrometry (ECD MS). Han, S. Y.; Lee, S. Y.; Oh, H. B. Bull. Korean Chem. Soc. 2005, 26, 740-746.

 

 
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